The potential interplay between G-quadruplex and p53: their roles in regulation of ferroptosis in cancer

Ferroptosis is a novel form of regulated cell death trigged by various biological processes, and p53 is involved in different ferroptosis regulations and functions as a crucial regulator. Both DNA and RNA can fold into G-quadruplex in GC-rich regions and increasing shreds of evidence demonstrate tha...

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Bibliographic Details

Published in:	Frontiers in Molecular Biosciences
Main Authors:	Lulu Zhang, Yi Lu, Xiaoli Ma, Yuanxin Xing, Jinbo Sun, Yanfei Jia
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-07-01
Subjects:	G-quadruplex p53 ferroptosis cancer biological activities
Online Access:	https://www.frontiersin.org/articles/10.3389/fmolb.2022.965924/full