Multiple umbilical cord–derived MSCs administrations attenuate rat osteoarthritis progression via preserving articular cartilage superficial layer cells and inhibiting synovitis

Background/objectives: Articular cartilage erosion probably plays a substantial role in osteoarthritis (OA) initiation and development. Studies demonstrated that umbilical cord–derived mesenchymal stem cells (UCMSCs) could delay chondrocytes apoptosis and ameliorate OA progression in patients, but t...

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Bibliographic Details

Published in:	Journal of Orthopaedic Translation
Main Authors:	Wei Tong, Xiaoguang Zhang, Quan Zhang, Jiarui Fang, Yong Liu, Zengwu Shao, Shuhua Yang, Dongcheng Wu, Xiaoming Sheng, Yingze Zhang, Hongtao Tian
Format:	Article
Language:	English
Published:	Elsevier 2020-07-01
Subjects:	Cartilage superficial layer cells Chondrocyte Osteoarthritis Synovitis Umbilical cord–derived mesenchymal stem cells
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214031X20300371