Selenium Status in Diet Affects Nephrotoxicity Induced by Cisplatin in Mice

Cisplatin is one of the most active chemotherapy drugs to treat solid tumors. However, it also causes various side effects, especially nephrotoxicity, in which oxidative stress plays critical roles. Our previous studies found that cisplatin selectively inhibited selenoenzyme thioredoxin reductase1 (...

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Bibliographic Details

Published in:	Antioxidants
Main Authors:	Shuang Liu, Xing Wen, Qihan Huang, Minghui Zhu, Jun Lu
Format:	Article
Language:	English
Published:	MDPI AG 2022-06-01
Subjects:	cisplatin nephrotoxicity oxidative stress thioredoxin selenium selenoprotein
Online Access:	https://www.mdpi.com/2076-3921/11/6/1141