Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide

Summary: The homeostatic regulation of serine palmitoyltransferase (SPT) activity in yeast involves N-terminal phosphorylation of Orm proteins, while higher eukaryotes lack these phosphorylation sites. Although recent studies have indicated a conserved ceramide-mediated feedback inhibition of the SP...

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出版年:	Cell Reports
主要な著者:	Tian Xie, Feitong Dong, Gongshe Han, Xinyue Wu, Peng Liu, Zike Zhang, Jianlong Zhong, Somashekarappa Niranjanakumari, Kenneth Gable, Sita D. Gupta, Wenchen Liu, Peter J. Harrison, Dominic J. Campopiano, Teresa M. Dunn, Xin Gong
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2024-02-01
主題:	CP: Molecular biology CP: Metabolism
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2211124724000457