Revealing the biological features of the axolotl pancreas as a new research model

IntroductionThe pancreas plays a crucial role in digestion and blood glucose regulation. Current animal models, primarily mice and zebrafish, have limited the exploration of pancreatic biology from an evolutionary-developmental perspective. Tetrapod vertebrate axolotl (Ambystoma mexicanum) serves as...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Hui Ma, Guangcong Peng, Yan Hu, Binbin Lu, Yiying Zheng, Yingxian Wu, Weimin Feng, Yu Shi, Xiangyu Pan, Li Song, Ina Stützer, Yanmei Liu, Jifeng Fei
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Subjects:	axolotl diabetes glucose metabolism pancreas development Pdx1 mutation
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1531903/full