LungGENIE: the lung gene-expression and network imputation engine

Abstract Background Few cohorts have study populations large enough to conduct molecular analysis of ex vivo lung tissue for genomic analyses. Transcriptome imputation is a non-invasive alternative with many potential applications. We present a novel transcriptome-imputation method called the Lung G...

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Bibliographic Details

Published in:	BMC Genomics
Main Authors:	Auyon J. Ghosh, Liam P. Coyne, Sanchit Panda, Aravind A. Menon, Matthew Moll, Michael A. Archer, Jason Wallen, Frank A. Middleton, Craig P. Hersh, Stephen J. Glatt, Jonathan L. Hess
Format:	Article
Language:	English
Published:	BMC 2025-03-01
Subjects:	Gene-expression Imputation Chronic obstructive pulmonary disease
Online Access:	https://doi.org/10.1186/s12864-025-11412-4