High-fat diet activates pyroptosis of retinal pigment epithelial cells in aged TgAPPswePS1 transgenic mice
Abstract Purpose This study assesses the impact of high-fat diet on retinal pigment epithelium (RPE) of aged TgAPPswePS1 transgenic mice, focusing on the involvement of RPE cell pyroptosis. Methods Twenty-four TgAPPswePS1 transgenic mice (18 months) was randomly divided into Tg group (n = 12) and Fa...
| Published in: | European Journal of Medical Research |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40001-025-02898-5 |