Revealing the Mechanisms of Shikonin Against Diabetic Wounds: A Combined Network Pharmacology and In Vitro Investigation

Conclusion: This study initially revealed the molecular mechanism of SHK in DW by multitarget and multipathway. The PI3K–AKT signaling pathway, MAPK signaling pathway, and AGE-RAGE signaling pathways may be the main pathways of SHK in treating DW.

Bibliographic Details

Published in:	Journal of Diabetes Research
Main Authors:	Meng Tian, Junchao Wu, Qian Du, Jiale Han, Meng Yang, Xiang Li, Mingzhu Li, Xiaofeng Ding, Yeqiang Song
Format:	Article
Language:	English
Published:	Wiley 2025-01-01
Online Access:	http://dx.doi.org/10.1155/jdr/4656485