Roles of C-reactive protein and LOX-1 on cancer and myeloid-derived suppressor cells in the progression of uterine cervical cancer

Abstract We investigated clinical implications of CRP and its receptor, LOX-1, in cervical cancer progression and the underlying mechanisms. Clinical data from 121 patients with cervical cancer administered definitive radiotherapy were analyzed to investigate the relationship among pretreatment seru...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Michihide Maeda, Seiji Mabuchi, Takashi Akazawa, Yu Mizote, Tomoyuki Sasano, Naoko Komura, Mina Sakata, Tsuyoshi Takiuchi, Shinya Matsuzaki, Tsuyoshi Hisa, Harumi Nakamura, Tomoya Ekawa, Shoji Kamiura, Tadashi Kimura, Hideaki Tahara
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-03-01
Subjects:	Cervical cancer C-reactive protein Inflammatory marker LOX-1 MDSCs Prognosis
Online Access:	https://doi.org/10.1038/s41598-025-91858-4