Click chemistry-based thiol redox proteomics reveals significant cysteine reduction induced by chronic ethanol consumption

In the U.S., alcohol-associated liver disease (ALD) impacts millions of people and is a major healthcare burden. While the pathology of ALD is unmistakable, the molecular mechanisms underlying ethanol hepatotoxicity are not fully understood. Hepatic ethanol metabolism is intimately linked with alter...

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Bibliographic Details

Published in:	Redox Biology
Main Authors:	Peter S. Harris, Courtney D. McGinnis, Cole R. Michel, John O. Marentette, Richard Reisdorph, James R. Roede, Kristofer S. Fritz
Format:	Article
Language:	English
Published:	Elsevier 2023-08-01
Subjects:	Cysteine Thiol Redox Proteomics Alcohol-associated liver disease Mass spectrometry
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231723001933