Proteomics-Based Identification of Interaction Partners of the Xenobiotic Detoxification Enzyme FMO3 Reveals Involvement in Urea Cycle

The hepatic xenobiotic metabolizing enzyme flavin-containing monooxygenase 3 (FMO3) has been implicated in the development of cardiometabolic disease primarily due to its enzymatic product trimethylamine-N oxide (TMAO), which has recently been shown to be associated with multiple chronic diseases, i...

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Bibliographic Details

Published in:	Toxics
Main Authors:	Zhao Yang, Paul M. Stemmer, Michael C. Petriello
Format:	Article
Language:	English
Published:	MDPI AG 2022-01-01
Subjects:	FMO3 urea cycle protein interactions TMAO proteomics
Online Access:	https://www.mdpi.com/2305-6304/10/2/60