Clinical characteristic of isolated thrombocytopenia in patients with bone marrow failure-related germline variants: a retrospective study from a single centre

Background Immune thrombocytopenia (ITP) comprises the majority of thrombocytopenia. Some patients respond poorly to first-line ITP therapy or develop pancytopenia years later. Recent studies link heterozygous germline variants in acquired aplastic anemia (AA), yet their role in isolated thrombocyto...

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Bibliographic Details

Published in:	Annals of Medicine
Main Authors:	Nanxi Dong, Jingjie Dong, Chuanao Xin, Peicheng Wang, Yaonan Hong, Rudan Zheng, Zexing Sun, Qi Liu, Yingying Shen, Xiawan Yang, Yiping Shen, Jianping Shen, Baodong Ye, Yuhong Zhou, Dijiong Wu
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2025-12-01
Subjects:	Heterozygous germline variants isolated thrombocytopenia mean corpuscular volume whole exome sequencing
Online Access:	https://www.tandfonline.com/doi/10.1080/07853890.2025.2523560