The Complex Work of Proteases and Secretases in Wallerian Degeneration: Beyond Neuregulin-1

After damage, axons in the peripheral nervous system (PNS) regenerate and regrow following a process termed Wallerian degeneration, but the regenerative process is often incomplete and usually the system does not reach full recovery. Key steps to the creation of a permissive environment for axonal r...

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Bibliographic Details

Published in:	Frontiers in Cellular Neuroscience
Main Authors:	Marta Pellegatta, Carla Taveggia
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-03-01
Subjects:	wallerian degeneration remyelination secretases matrix metalloproteinases fibrinolysis
Online Access:	https://www.frontiersin.org/article/10.3389/fncel.2019.00093/full