Combined metabolome and transcriptome to analyze the regulatory network of key enzymes in the synthesis of senkirkine in Emilia sonchifolia

Abstract Emilia sonchifolia (L.) DC. serves as a well-known folk medicinal and edible plant, yet its toxic component senkirkine exhibits hepatotoxicity. Acute high-dose exposure can induce sinusoidal obstruction syndrome, while chronic low-dose intake may cause hepatic megaloblastosis and fibrosis....

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Bibliographic Details

Published in:	BMC Plant Biology
Main Authors:	Jinli Yao, Yanqing Qin, Dongping Tu, Yumei Huang, Liuguan Liang, Wenhui Cai, Mingli Huang, Xiaoqi Zhu, Xinling Lao
Format:	Article
Language:	English
Published:	BMC 2025-08-01
Subjects:	Emilia sonchifolia Senkirkine Metabolome Transcriptome QRT-PCR
Online Access:	https://doi.org/10.1186/s12870-025-07079-4