Peptides That Block RAS-p21 Protein-Induced Cell Transformation

This is a review of approaches to the design of peptides and small molecules that selectively block the oncogenic RAS-p21 protein in ras-induced cancers. Single amino acid substitutions in this protein, at critical positions such as at Gly 12 and Gln 61, cause the protein to become oncogenic. These...

全面介紹

書目詳細資料

發表在:	Biomedicines
Main Authors:	Matthew R. Pincus, Bo Lin, Purvi Patel, Elmer Gabutan, Nitzan Zohar, Wilbur B. Bowne
格式:	Article
語言:	英语
出版:	MDPI AG 2023-02-01
主題:	RAS-p21 protein oncogenic forms peptides small molecules amino acid substitutions mutant protein
在線閱讀:	https://www.mdpi.com/2227-9059/11/2/471