BIT: Bayesian Identification of Transcriptional regulators from epigenomics-based query region sets

Abstract Transcriptional regulators (TRs) are master controllers of gene expression and play a critical role in both normal tissue development and disease progression. However, existing computational methods for identification of TRs regulating specific biological processes have significant limitati...

詳細記述

書誌詳細
出版年:Nature Communications
主要な著者: Zeyu Lu, Lin Xu, Xinlei Wang
フォーマット: 論文
言語:英語
出版事項: Nature Portfolio 2025-05-01
オンライン・アクセス:https://doi.org/10.1038/s41467-025-60269-4