Rezafungin treatment in mouse models of invasive candidiasis and aspergillosis: Insights on the PK/PD pharmacometrics of rezafungin efficacy

Abstract Rezafungin acetate is a novel echinocandin in clinical development for prevention and treatment of invasive fungal infections. Rezafungin is differentiated by a pharmacokinetic/pharmacodynamic (PK/PD) profile that includes a long half‐life allowing once‐weekly administration, front‐loaded p...

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Bibliographic Details

Published in:	Pharmacology Research & Perspectives
Main Authors:	Lynn Miesel, Kun‐Yuan Lin, Voon Ong
Format:	Article
Language:	English
Published:	Wiley 2019-12-01
Subjects:	antifungal treatment Aspergillus azole resistance Candida CD101 echinocandin
Online Access:	https://doi.org/10.1002/prp2.546