Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids.

BACKGROUND: The glucocorticoid receptor (GR) is a transcription factor that regulates gene expression in a ligand-dependent fashion. This modular protein is one of the major pharmacological targets due to its involvement in both cause and treatment of many human diseases. Intense efforts have been m...

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發表在:	PLoS ONE
Main Authors:	Diego M Presman, Lautaro D Alvarez, Valeria Levi, Silvina Eduardo, Michelle A Digman, Marcelo A Martí, Adriana S Veleiro, Gerardo Burton, Adali Pecci
格式:	Article
語言:	英语
出版:	Public Library of Science (PLoS) 2010-01-01
在線閱讀:	http://europepmc.org/articles/PMC2952596?pdf=render