Deciphering the role of signal regulatory protein α in immunotherapy for solid tumors

Therapies targeting immune checkpoints like programmed death receptor-1 and programmed death ligand-1 have demonstrated remarkable effectiveness in combating cancer. However, a subset of patients fails to respond to these therapies, underscoring the complexity of tumor immune evasion mechanisms. Exp...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Yulong Zhou, Xiyang Tang, Weiguang Du, Chen Shu, Xiaolong Yan, Nan Ma, Jinbo Zhao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Subjects:	CD47 immunotherapy immune checkpoint inhibitor SIRPα solid tumor
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1612234/full