Pharmacological targeting of smoothened receptor cysteine-rich domain by Budesonide promotes in vitro myelination

BackgroundThe myelin sheath ensures efficient nerve impulse transmission along the axons. Remyelination is a spontaneous process that restores axonal insulation, promoting neuroprotection and recovery after myelin damage. There is an urgent need for new pharmacological approaches to remyelination an...

詳細記述

書誌詳細

出版年:	Frontiers in Molecular Neuroscience
主要な著者:	Antonella Damiana Recchia, Alessandra Dominicis, Vincenzo Maria D'Amore, Tommaso Fabiano, Aland Ibrahim Ahmed Al Jaf, Simone Peria, Francesco Basoli, Alberto Rainer, Luciana Marinelli, Francesco Saverio Di Leva, Antonella Ragnini-Wilson
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2024-10-01
主題:	remyelination oligodendrocytes glucocorticoids molecular docking & molecular dynamics (MD) simulation glia cells hedgehog (Hh)
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fnmol.2024.1473960/full