A fingerprint of 2-[18F]FDG radiometabolites – How tissue-specific metabolism beyond 2-[18F]FDG-6-P could affect tracer accumulation

Summary: Studies indicate that the radiotracer 2-[18F]fluoro-2-deoxy-D-glucose (2-[18F]FDG) can be metabolized beyond 2-[18F]FDG-6-phosphate (2-[18F]FDG-6-P), but its metabolism is incompletely understood. Most importantly, it remains unclear whether downstream metabolism affects tracer accumulation...

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Bibliographic Details

Published in:	iScience
Main Authors:	Eva-Maria Patronas, Theresa Balber, Anne Miller, Barbara Katharina Geist, Antje Michligk, Chrysoula Vraka, Maximilian Krisch, Nataliya Rohr-Udilova, Arvand Haschemi, Helmut Viernstein, Marcus Hacker, Markus Mitterhauser
Format:	Article
Language:	English
Published:	Elsevier 2023-11-01
Subjects:	nuclear medicine radiochemicals cancer
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004223022149