Inhibition of ASCT2 is essential in all‐trans retinoic acid‐induced reduction of adipogenesis in 3T3‐L1 cells

Vitamin A has preventive effects on obesity. All‐trans retinoic acid (ATRA), the active form of vitamin A, inhibits lipid accumulation in 3T3‐L1 cells in an experimental adipogenesis model. We found that ATRA suppressed up‐regulation of the amino acid transporter, Asct2, in adipogenerating 3T3‐L1 ce...

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Bibliographic Details
Published in:FEBS Open Bio
Main Authors: Katsuhiko Takahashi, Natsumi Uchida, Chisato Kitanaka, Chiaki Sagara, Masahiko Imai, Noriko Takahashi
Format: Article
Language:English
Published: Wiley 2015-01-01
Subjects:
Adipocyte
All-trans retinoic acid
Asct2
l-glutamine
Obesity
Online Access:https://doi.org/10.1016/j.fob.2015.06.012

Internet

https://doi.org/10.1016/j.fob.2015.06.012

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