Compartmentalization and Trafficking in Endoplasmic Reticulum Protein Quality Control

Following translocation into the rough endoplasmic reticulum (ER), secretory proteins undergo a series of folding, maturation, compartmentalization and trafficking events. These are finely tuned to avoid misfolded protein accumulation and the consequent ER stress. Misfolded proteins and components o...

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Bibliographic Details
Published in:Biology and Life Sciences Forum
Main Author: Gerardo Z. Lederkremer
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Subjects:
endoplasmic reticulum
ERAD
vesicular trafficking
Online Access:https://www.mdpi.com/2673-9976/21/1/10

Internet

https://www.mdpi.com/2673-9976/21/1/10

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