MOSBY enables multi-omic inference and spatial biomarker discovery from whole slide images

Abstract The utility of deep neural nets has been demonstrated for mapping hematoxylin-and-eosin (H&E) stained image features to expression of individual genes. However, these models have not been employed to discover clinically relevant spatial biomarkers. Here we develop MOSBY (Multi-Omic tran...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Yasin Şenbabaoğlu, Vignesh Prabhakar, Aminollah Khormali, Jeff Eastham, Evan Liu, Elisa Warner, Barzin Nabet, Minu Srivastava, Marcus Ballinger, Kai Liu
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-08-01
Online Access:	https://doi.org/10.1038/s41598-024-69198-6