Targeting STAT3 in Cancer Immunotherapy

Abstract As a point of convergence for numerous oncogenic signaling pathways, signal transducer and activator of transcription 3 (STAT3) is central in regulating the anti-tumor immune response. STAT3 is broadly hyperactivated both in cancer and non-cancerous cells within the tumor ecosystem and play...

Full description

Bibliographic Details
Published in:Molecular Cancer
Main Authors: Sailan Zou, Qiyu Tong, Bowen Liu, Wei Huang, Yan Tian, Xianghui Fu
Format: Article
Language:English
Published: BMC 2020-09-01
Subjects:
STAT3
Cancer
Immunosuppression
Immunotherapy
Immune checkpoint blockade
CAR-T
Online Access:http://link.springer.com/article/10.1186/s12943-020-01258-7

Internet

http://link.springer.com/article/10.1186/s12943-020-01258-7

Similar Items