Remdesivir postexposure prophylaxis limits measles-induced “immune amnesia” and measles antibody responses in macaques

Measles remains one of the most important causes of worldwide morbidity and mortality in children. Measles virus (MeV) replicates extensively in lymphoid tissue, and most deaths are due to other infectious diseases associated with MeV-induced loss of circulating antibodies to other pathogens. To det...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Andy Kwan Pui Chan, Liting Liu, William R. Morgenlander, Manjusha Thakar, Nadine A. Peart Akindele, Jacqueline Brockhurst, Shristi Ghimire, Maggie L. Bartlett, Kelly A. Metcalf Pate, Victor C. Chu, Meghan S. Vermillion, Danielle P. Porter, Tomas Cihlar, Michael J. Mina, H. Benjamin Larman, Diane E. Griffin
Format: Article
Language:English
Published: American Society for Clinical investigation 2025-06-01
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Online Access:https://doi.org/10.1172/jci.insight.190740