Safety and infectivity of female cercariae in Schistosoma-naïve, healthy participants: a controlled human Schistosoma mansoni infection studyResearch in context

Summary: Background: A controlled human infection model for schistosomiasis (CHI-S) can speed up vaccine development and provides insight into early immune responses following schistosome exposure. Recently, we established CHI-S model using single-sex male-only Schistosoma mansoni (Sm) cercariae in...

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Bibliographic Details

Published in:	EBioMedicine
Main Authors:	Jan Pieter R. Koopman, Emma L. Houlder, Jacqueline J. Janse, Miriam Casacuberta-Partal, Olivia A.C. Lamers, Jeroen C. Sijtsma, Claudia de Dood, Stan T. Hilt, Arifa Ozir-Fazalalikhan, Vincent P. Kuiper, Geert V.T. Roozen, Laura M. de Bes-Roeleveld, Yvonne C.M. Kruize, Linda J. Wammes, Hermelijn H. Smits, Lisette van Lieshout, Govert J. van Dam, Inge M. van Amerongen-Westra, Pauline Meij, Paul L.A.M. Corstjens, Simon P. Jochems, Angela van Diepen, Maria Yazdanbakhsh, Cornelis H. Hokke, Meta Roestenberg
Format:	Article
Language:	English
Published:	Elsevier 2023-11-01
Subjects:	Controlled human infection model Neglected tropical diseases Schistosomiasis Schistosoma mansoni
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396423003985