Prenatal Lipopolysaccharide Exposure Alters Hepatic Drug-Metabolizing Enzyme Expression in Mouse Offspring via Histone Modifications

Inflammation is a major regulator of drug-metabolizing enzymes (DMEs), therefore contributing to the interindividual variability of drug effects. However, whether prenatal inflammation affects DMEs expression in offspring remains obscure. This study investigated the effects of prenatal lipopolysacch...

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Bibliographic Details

Published in:	Toxics
Main Authors:	Hanhan Zhu, Guangming Liu, Qi Chang, Mengyao Yan, Kun Yang, Yanxin Li, Yali Nie, Xiaotian Li, Shengna Han, Pei Wang, Lirong Zhang
Format:	Article
Language:	English
Published:	MDPI AG 2023-01-01
Subjects:	inflammation lipopolysaccharides drug-metabolizing enzyme histone modification
Online Access:	https://www.mdpi.com/2305-6304/11/1/82