Formulation Design, Statistical Optimization, and In Vitro Evaluation of a Naringenin Nanoemulsion to Enhance Apoptotic Activity in A549 Lung Cancer Cells

Naringenin (NAR), a flavonoid mainly found in citrus and grapefruits, has proven anti-cancer activities. However, the poor water solubility and low bioavailability of NAR limits its use as a therapeutic agent. The aim of this study was to develop and optimize stable naringenin nanoemulsions (NAR-NE)...

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Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Shadab Md, Nabil A. Alhakamy, Hibah M. Aldawsari, Mohammad Husain, Sabna Kotta, Samaa T. Abdullah, Usama A. Fahmy, Mohamed A. Alfaleh, Hani Z. Asfour
Format:	Article
Language:	English
Published:	MDPI AG 2020-07-01
Subjects:	apoptosis Box–Behnken design naringenin natural product lung cancer
Online Access:	https://www.mdpi.com/1424-8247/13/7/152