Enhanced 2-keto-l-gulonic acid production by applying l-sorbose-tolerant helper strain in the co-culture system

Abstract 2-Keto-l-gulonic acid (the precursor of vitamin C) is bio-converted from l-sorbose by mixed fermentation of Ketogulonicigenium vulgare and a helper strain. The helper strain promotes the conversion of 2-KLG by enhancing the growth of K. vulgare, but its growth is greatly inhibited by high c...

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Bibliographic Details

Published in:	AMB Express
Main Authors:	Mandlaa, Ziyu Sun, Ruigang Wang, Xiaodong Han, Hui Xu, Weichao Yang
Format:	Article
Language:	English
Published:	SpringerOpen 2018-02-01
Subjects:	2-Keto-gulonic acid Co-culture system Helper strain l-Sorbose Vitamin C
Online Access:	http://link.springer.com/article/10.1186/s13568-018-0562-y