Knockdown of ANGPTL-4 inhibits inflammatory response and extracellular matrix accumulation in glomerular mesangial cells cultured under high glucose condition

Diabetic nephropathy (DN) is one of the major diabetic complications that lead to end-stage renal failure. Angiopoietin-like protein-4 (ANGPTL-4) has been reported to be dysregulated in diabetes mellitus and diabetic complications. However, the role of ANGPTL-4 in glomerular mesangial cells (MCs) du...

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Bibliographic Details

Published in:	Artificial Cells, Nanomedicine, and Biotechnology
Main Authors:	Linfang Qin, Ruimin Zhang, Suxia Yang, Fang Chen, Jun Shi
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2019-12-01
Subjects:	Diabetic nephropathy (DN) diabetes mellitus glomerular mesangial cells (MCs) angiopoietin-like protein-4 (ANGPTL-4) extracellular matrix (ECM) inflammation
Online Access:	https://www.tandfonline.com/doi/10.1080/21691401.2019.1649274