Ubiquitylation, neddylation and the DNA damage response

Failure of accurate DNA damage sensing and repair mechanisms manifests as a variety of human diseases, including neurodegenerative disorders, immunodeficiency, infertility and cancer. The accuracy and efficiency of DNA damage detection and repair, collectively termed the DNA damage response (DDR), r...

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Bibliographic Details

Published in:	Open Biology
Main Authors:	Jessica S. Brown, Stephen P. Jackson
Format:	Article
Language:	English
Published:	The Royal Society 2015-01-01
Subjects:	dna damage response double-strand break repair ubiquitin nedd8 mln4924
Online Access:	https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.150018