Canine intestinal organoids as a platform for studying MHC class II expression in epithelial cells

Abstract Backgrounds The interplay between intestinal epithelial cells (IECs), the immune system, and the gut microbiome is pivotal for maintaining gastrointestinal homeostasis and mediating responses to ingested antigens. IECs, capable of expressing Major Histocompatibility Complex (MHC) class II m...

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Bibliographic Details
Published in:BMC Molecular and Cell Biology
Main Authors: Meg Nakazawa, Itsuma Nagao, Yoko M. Ambrosini
Format: Article
Language:English
Published: BMC 2025-04-01
Subjects:
Canine
Intestinal epithelial cells
Intestinal organoids
MHC class II
IFN-γ
Translational medicine
Online Access:https://doi.org/10.1186/s12860-025-00536-w

Internet

https://doi.org/10.1186/s12860-025-00536-w

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