Quantification of human papillomavirus cell-free DNA from low-volume blood plasma samples by digital PCR

ABSTRACT The incidence rate of human papillomavirus-driven oropharyngeal cancer (HPV-OPC) is increasing in countries with high human development index. HPV cell-free DNA (cfDNA) isolated from 3 to 4 mL blood plasma has been successfully used for therapy surveillance. A highly discussed application o...

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Bibliographic Details

Published in:	Microbiology Spectrum
Main Authors:	Fabian Rosing, Matthias Meier, Lea Schroeder, Simon Laban, Thomas Hoffmann, Andreas Kaufmann, Oliver Siefer, Nora Wuerdemann, Jens Peter Klußmann, Thorsten Rieckmann, Yvonne Alt, Daniel L. Faden, Tim Waterboer, Daniela Höfler
Format:	Article
Language:	English
Published:	American Society for Microbiology 2024-07-01
Subjects:	HPV liquid biopsy digital PCR OPC cfDNA early detection
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.00024-24