Effects of all-trans retinoic acid and oxygen concentration on the proliferation and differentiation of subcutaneous adipocytes in yak

In this study, we investigated the mechanism by which all-trans retinoic acid (ATRA) regulates the hypoxic adaptation of yak subcutaneous adipocytes through a dose-dependent regulation. The effects of different concentrations of ATRA (10 nM−10 μM) on cell proliferation and differentiation, lipid met...

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Bibliographic Details

Published in:	Frontiers in Veterinary Science
Main Authors:	Sibinuer Yasenjian, Su Shan, Yuqi Zhe, Yuqing Zhang, Zhixin Chai
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Subjects:	yak subcutaneous adipocytes all-trans retinoic acid proliferation differentiation hypoxia adaptation
Online Access:	https://www.frontiersin.org/articles/10.3389/fvets.2025.1643818/full