Host-versus-commensal immune responses participate in the rejection of colonized solid organ transplants

Solid organ transplantation is the preferred treatment for end-stage organ failure. Although transplant recipients take life-long immunosuppressive drugs, a substantial percentage of them still reject their allografts. Strikingly, barrier organs colonized with microbiota have significantly shorter h...

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Bibliographic Details

Published in:	The Journal of Clinical Investigation
Main Authors:	Isabella Pirozzolo, Martin Sepulveda, Luqiu Chen, Ying Wang, Yuk Man Lei, Zhipeng Li, Rena Li, Husain Sattar, Betty Theriault, Yasmine Belkaid, Anita S. Chong, Maria-Luisa Alegre
Format:	Article
Language:	English
Published:	American Society for Clinical Investigation 2022-09-01
Subjects:	Immunology Transplantation
Online Access:	https://doi.org/10.1172/JCI153403