The Wilms Tumor Gene wt1a Contributes to Blood-Cerebrospinal Fluid Barrier Function in Zebrafish

The Wilms tumor suppressor gene Wt1 encodes a zinc finger transcription factor, which is highly conserved among vertebrates. It is a key regulator of urogenital development and homeostasis but also plays a role in other organs including the spleen and the heart. More recently additional functions fo...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Vera L. Hopfenmüller, Birgit Perner, Hanna Reuter, Thomas J. D. Bates, Andreas Große, Christoph Englert
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-01-01
Subjects:	Wilms tumor protein zebrafish choroid plexus CRISPR/cas9 dye accumulation assay fluorescent tracer
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2021.809962/full