Network toxicology and bioinformatics analysis reveal the molecular mechanisms of polyethylene terephthalate microplastics in exacerbating diabetic nephropathy

Abstract The escalating prevalence of diabetic nephropathy (DN) has raised concerns about environmental pollutants, particularly polyethylene terephthalate microplastics (PET-MP), as potential contributors to metabolic diseases. However, the molecular mechanisms linking PET-MP exposure to DN remain...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Shengnan Zeng, Hui Guo
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-06-01
Subjects:	Polyethylene terephthalate microplastics Diabetic nephropathy Toxicology Molecular pathways Machine learning Molecular Docking
Online Access:	https://doi.org/10.1038/s41598-025-03285-0