Virtual Biopsy for the Prediction of MGMT Promoter Methylation in Gliomas: A Comprehensive Review of Radiomics and Deep Learning Approaches Applied to MRI

<b>Background/Objectives</b>: The methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) promoter in gliomas has emerged as a critical biomarker for prognosis and treatment response. Conventional methods for assessing MGMT promoter methylation, such as methylation-specif...

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Bibliographic Details
Published in:Diagnostics
Main Authors: Augusto Leone, Veronica Di Napoli, Nicola Pio Fochi, Giuseppe Di Perna, Uwe Spetzger, Elena Filimonova, Flavio Angileri, Francesco Carbone, Antonio Colamaria
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Subjects:
radiomics
deep learning
machine learning
O6-methylguanine-DNA methyltransferase
gliomas
non-invasive diagnostics
Online Access:https://www.mdpi.com/2075-4418/15/3/251

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https://www.mdpi.com/2075-4418/15/3/251

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