Bacterial pore-forming toxin pneumolysin drives pathogenicity through host extracellular vesicles released during infection

Summary: Streptococcus pneumoniae is a global priority respiratory pathogen that kills over a million people annually. The pore-forming cytotoxin, pneumolysin (PLY) is a major virulence factor. Here, we found that recombinant PLY as well as wild-type pneumococcal strains, but not the isogenic PLY mu...

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發表在:	iScience
Main Authors:	Saba Parveen, Chinmayi V. Bhat, Aswathy C. Sagilkumar, Shaheena Aziz, J. Arya, Asmita Dutta, Somit Dutta, Sautan Show, Kuldeep Sharma, Sumit Rakshit, John Bernet Johnson, Upendra Nongthomba, Anirban Banerjee, Karthik Subramanian
格式:	Article
語言:	英语
出版:	Elsevier 2024-08-01
主題:	Microbiology Bacteriology Cell biology
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2589004224018145