Stabilization mechanism accommodating genome length variation in evolutionarily related viral capsids

Abstract Tailed bacteriophages are one of the most numerous and diverse group of viruses. They store their genome at quasi-crystalline densities in capsids built from multiple copies of proteins adopting the HK97-fold. The high density of the genome exerts an internal pressure, requiring a maturatio...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Jennifer M. Podgorski, Joshua Podgorski, Lawrence Abad, Deborah Jacobs-Sera, Krista G. Freeman, Colin Brown, Graham F. Hatfull, Antoni Luque, Simon J. White
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-04-01
Online Access:	https://doi.org/10.1038/s41467-025-58298-0