Vendor effects on murine gut microbiota and its influence on lipopolysaccharide-induced lung inflammation and Gram-negative pneumonia

Abstract Background The microbiome has emerged as an important player in the pathophysiology of a whole spectrum of diseases that affect the critically ill. We hypothesized that differences in microbiota composition across vendors can influence murine models of pulmonary lipopolysaccharide (LPS) inf...

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Bibliographic Details

Published in:	Intensive Care Medicine Experimental
Main Authors:	Nora S. Wolff, Max C. Jacobs, Bastiaan W. Haak, Joris J. T. H. Roelofs, Alex F. de Vos, Floor Hugenholtz, W. Joost Wiersinga
Format:	Article
Language:	English
Published:	SpringerOpen 2020-08-01
Subjects:	Intestinal microbiota Vendor Lipopolysaccharide Klebsiella pneumoniae Pulmonary Inflammation Infection
Online Access:	http://link.springer.com/article/10.1186/s40635-020-00336-w