Secretive derived from hypoxia preconditioned mesenchymal stem cells promote cartilage regeneration and mitigate joint inflammation via extracellular vesicles

Secretome derived from mesenchymal stem cells (MSCs) have profound effects on tissue regeneration, which could become the basis of future MSCs therapies. Hypoxia, as the physiologic environment of MSCs, has great potential to enhance MSCs paracrine therapeutic effect. In our study, the paracrine eff...

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Bibliographic Details

Published in:	Bioactive Materials
Main Authors:	Yanmeng Yang, Yingnan Wu, Dahou Yang, Shu Hui Neo, Nurul Dinah Kadir, Doreen Goh, Jian Xiong Tan, Vinitha Denslin, Eng Hin Lee, Zheng Yang
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2023-09-01
Subjects:	Hypoxia preconditioned MSCs Secretome Extracellular vesicles Cartilage regeneration Joint inflammation
Online Access:	http://www.sciencedirect.com/science/article/pii/S2452199X23001111