mRNA vaccine for cancer immunotherapy

Abstract mRNA vaccines have become a promising platform for cancer immunotherapy. During vaccination, naked or vehicle loaded mRNA vaccines efficiently express tumor antigens in antigen-presenting cells (APCs), facilitate APC activation and innate/adaptive immune stimulation. mRNA cancer vaccine pre...

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Bibliographic Details
Published in:Molecular Cancer
Main Authors: Lei Miao, Yu Zhang, Leaf Huang
Format: Article
Language:English
Published: BMC 2021-02-01
Subjects:
Online Access:https://doi.org/10.1186/s12943-021-01335-5