Development of a RP-HPLC method for evaluation of in vitro permeability of voriconazole in the presence of enhancers through rat skin

Abstract An isocratic RP-HPLC–UV method for the analysis of voriconazole in skin diffusate samples has been developed and validated. Experimental design was employed to optimize the method. The method was validated as per ICH guidelines. Linearity was observed over the concentration range of 2–100 μ...

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Bibliographic Details

Published in:	Journal of Saudi Chemical Society
Main Authors:	M. Vamsi Krishna, Rajendra N. Dash, P. Venugopal, B. Jalachandra Reddy, P. Sandeep, G. Madhavi
Format:	Article
Language:	English
Published:	Springer 2013-07-01
Subjects:	Voriconazole RP-HPLC Permeation enhancers Skin diffusate samples
Online Access:	https://doi.org/10.1016/j.jscs.2013.07.003