Transduction of SIV-specific TCR genes into rhesus macaque CD8+ T cells conveys the ability to suppress SIV replication.

<h4>Background</h4>The SIV/rhesus macaque model for HIV/AIDS is a powerful system for examining the contribution of T cells in the control of AIDS viruses. To better our understanding of CD8(+) T-cell control of SIV replication in CD4(+) T cells, we asked whether TCRs isolated from rhesu...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Eugene V Barsov, Matthew T Trivett, Jacob T Minang, Haosi Sun, Claes Ohlen, David E Ott
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-01-01
Online Access:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0023703&type=printable