Optimal combination of arsenic trioxide and copper ions to prevent autoimmunity in a murine HOCl-induced model of systemic sclerosis

IntroductionSystemic sclerosis (SSc) is a rare chronic autoimmune disease characterized by diffuse fibrosis of the skin and internal organs and vascular abnormalities. The etiology and physiopathology are complex due to the heterogeneity of its overall clinical presentation. Arsenic trioxide (ATO) h...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Charlotte Chêne, Dominique Rongvaux-Gaïda, Marine Thomas, François Rieger, Carole Nicco, Frédéric Batteux
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Subjects:	arsenic trioxide ATO copper fenton-like reaction fibrosis systemic sclerosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1149869/full