Size matters in telomere biology disorders ‒ expanding phenotypic spectrum in patients with long or short telomeres

Abstract The end of each chromosome consists of a DNA region termed the telomeres. The telomeres serve as a protective shield against degradation of the coding DNA sequence, as the DNA strand inevitably ‒ with each cell division ‒ is shortened. Inherited genetic variants cause telomere biology disor...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Hereditary Cancer in Clinical Practice
المؤلفون الرئيسيون:	Anna Byrjalsen, Anna Engell Brainin, Thomas Kromann Lund, Mette Klarskov Andersen, Anne Marie Jelsig
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	BMC 2023-05-01
الموضوعات:	Telomere biology disorders Lung fibrosis Cancer predisposition Long telomeres Short telomeres
الوصول للمادة أونلاين:	https://doi.org/10.1186/s13053-023-00251-7