In mitosis integrins reduce adhesion to extracellular matrix and strengthen adhesion to adjacent cells

Abstract To enter mitosis, most adherent animal cells reduce adhesion, which is followed by cell rounding. How mitotic cells regulate adhesion to neighboring cells and extracellular matrix (ECM) proteins is poorly understood. Here we report that, similar to interphase, mitotic cells can employ integ...

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التفاصيل البيبلوغرافية
الحاوية / القاعدة:Nature Communications
المؤلفون الرئيسيون: Maximilian Huber, Javier Casares-Arias, Reinhard Fässler, Daniel J. Müller, Nico Strohmeyer
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Nature Portfolio 2023-04-01
الوصول للمادة أونلاين:https://doi.org/10.1038/s41467-023-37760-x