Snowflake: A deep learning-based human leukocyte antigen matching algorithm considering allele-specific surface accessibility

Histocompatibility in solid-organ transplantation has a strong impact on long-term graft survival. Although recent advances in matching of both B-cell epitopes and T-cell epitopes have improved understanding of allorecognition, the immunogenic determinants are still not fully understood. We hypothes...

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書目詳細資料
發表在:Frontiers in Immunology
Main Authors: Matthias Niemann, Benedict M. Matern, Eric Spierings
格式: Article
語言:英语
出版: Frontiers Media S.A. 2022-07-01
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在線閱讀:https://www.frontiersin.org/articles/10.3389/fimmu.2022.937587/full